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  In article &lt;Cun2AA....@tfs.com&gt;, poy...@tfs.com (David Poyner) says: &lt;br /&gt; &lt;p&gt;&gt;Nancy VonStein (nvonst...@cc.memphis.edu) wrote: &lt;br /&gt; &gt;: There was an article posted here about a month ago about the collection &lt;br /&gt; &gt;: of Premarin. &#160;I thought I had kept it but can&#039;t find it now. &#160;If anyone &lt;br /&gt; &gt;: can send me that article, I would appreciate it greatly. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;&gt;I heard the horror story second-hand. It&#039;s made from mares&#039; urine and the &lt;br /&gt; &gt;poor things are kept in cages in Canada, yes? I&#039;d appreciate a re-post if &lt;br /&gt; &gt;anyone could oblige. &lt;br /&gt; &lt;br /&gt;------------------------------------------------------ &lt;br /&gt; Subject: PETA Article On Abuse of Horses To Produce Premarin &lt;br /&gt; &lt;/p&gt;&lt;p&gt;Premarin stands for PREgnant MARes UrINe. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;-------------------------- Message Contents ------------------------------ &#160; &#160; - &lt;br /&gt; &lt;/p&gt;&lt;p&gt;Taken from PETA&#039;s &quot;Premarin Menopause Drug Nightmare&quot; brochure. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;As the &quot;Baby Boomer&quot; generation matures, and more and more women find &lt;br /&gt; themselves undergoing &quot;The change of life,&quot; many will be advised by &lt;br /&gt; their doctors to take an estrogen replacement drug to alleviate &lt;br /&gt; menopausal symptoms. &#160;But the drug most commonly prescribed has at &lt;br /&gt; least one ugly side effect: cruelty. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;The drug is Premarin, an estrogen substitute extracted from the urine &lt;br /&gt; of pregnant mares. &#160;It is routinely prescribed for women who have had &lt;br /&gt; hysterectomies or are experiencing menopausal symptoms, and also for &lt;br /&gt; post-menopausal women to prevent osteoporosis and heart disease. &#160;With &lt;br /&gt; an estimated eight million women currently taking the drug, and some &lt;br /&gt; 43,000,000 women entering menopause,, the pregnant mare urine (PMU) &lt;br /&gt; industry is booming. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;While this spells profits for Canada-based Ayerst Organics, Inc., the &lt;br /&gt; world&#039;s only producer of PMU, it also spells misery and death for &lt;br /&gt; hundreds of thousands of horses and foals. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;To produce the drug, mares are impregnated, then catheterized or fitted &lt;br /&gt; with a rubber collection cup attached to a hose. &#160;Because allowing &lt;br /&gt; mares out to pasture would mean losing some of their precious urine, &lt;br /&gt; they are forced to stand on concrete floors in stalls measuring just 8 &lt;br /&gt; feet long and 3.5 to 5 feet wide for most of their 11-month &lt;br /&gt; pregnancies. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;For more than half the year -- from September to April -- the mares &lt;br /&gt; are unable to take more than a step in any direction, the narrowness &lt;br /&gt; of their stall preventing even such simple movements ads turning &lt;br /&gt; around or lying down properly. &#160;Farmers who have leased their horses &lt;br /&gt; to PMU facilities report mares returning crippled and in poor health, &lt;br /&gt; and one former farm employee documented several deaths on the Manitoba &lt;br /&gt; farm where he worked. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;After giving birth, the mares are allowed only 2 months to pasture &lt;br /&gt; with their foals, during which time they are reimpregnated, then &lt;br /&gt; separated from their babies, and put back on the production line. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;Like calves taken away from their &quot;dairy cow&quot; mothers to be raised for &lt;br /&gt; veal, the mares&#039; foals are merely a &quot;by-product&quot; of PMU production. &lt;br /&gt; Some are killed immediately, others are kept as replacements for &lt;br /&gt; worn-out mares or to expand production; &#160;the majority are sold when &lt;br /&gt; they are about four months old, sent to feedlots to be fattened, and &lt;br /&gt; then slaughtered. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;The cruelty of the PMU industry has caused an outcry from North &lt;br /&gt; Americans, including animal rights activists and women&#039;s groups. &lt;br /&gt; Problems with the manufacturing process, especially the disposal of &lt;br /&gt; its foul-smelling waste products, worry Canadian environmentalists &lt;br /&gt; and legislators. &#160;Proposed expansion at Ayerst&#039;s Manitoba production &lt;br /&gt; facility threatens to overwhelm and already taxed sewage treatment &lt;br /&gt; system. &#160;In addition, according to Marianne Cerilli, member of the &lt;br /&gt; Legislative Assembly and Environment Critic for the Canadian New &lt;br /&gt; Democratic Party, the expansion has &quot;serious consequences for the &lt;br /&gt; Assinboine River, a river that many Manitobans use as a drinking water &lt;br /&gt; source.&quot; &#160;Hormone therapy itself is coming under increasing scrutiny &lt;br /&gt; because of possible health risks. &#160;Studies have shown that women on &lt;br /&gt; hormone replacement drugs have an increased risk of gall bladder &lt;br /&gt; disease and endometrial and breast cancers and suffer a range of side &lt;br /&gt; effects, such as water retention, cramps, and headaches. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;Since synthetic estrogen can now be manufactured inexpensively, &lt;br /&gt; collecting PMU is an antiquated method of producing estrogen. &lt;br /&gt; Premarin is the only menopause drug still made with animal-derived &lt;br /&gt; estrogen, and other synthetic estrogens, such as Estradiol &lt;br /&gt; Transdermal System, Estradiol tablets, Estropipate, and Estone, are &lt;br /&gt; equally effective. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;In response to Canadian animal protectionists, who were success ful in &lt;br /&gt; shutting down the PMU industry in Ontario during the 1970&#039;s, the &lt;br /&gt; industry devised a Recommended Code of Practice, which outlines basic &lt;br /&gt; care for horses used for urine production. &#160;However, this code merely &lt;br /&gt; contains recommendations -- no farmer is required to follow them -- &lt;br /&gt; and even these basic standards are so weak they fail to provide &lt;br /&gt; horses with even minimal protection. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;In 1993, an estimated 75,000 mares on 485 farms throughout Canada and &lt;br /&gt; North Dakota were confined for urine collection, giving birth to as &lt;br /&gt; many as 90,000 foals -- and the number may triple in the next few &lt;br /&gt; years if women continue to want non-synthetic treatments. &#160;Already, &lt;br /&gt; another 1,200 farms have applied to produce PMU, for which they are &lt;br /&gt; paid up to $17 a gallon. &#160;Ayerst is preparing for a $100 million &lt;br /&gt; expansion of its facilities in Manitoba with the aid of $20 million &lt;br /&gt; form the Canadian government. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;WHAT YOU CAN DO: &lt;br /&gt; =-=-=-=-=-=-=-= &lt;br /&gt; &lt;/p&gt;&lt;p&gt;- Write a simple letter to a health/women&#039;s magazine and your local &lt;br /&gt; paper explaining how mare&#039;s urine is acquired an that there are safe &lt;br /&gt; synthetics available. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;- Because of th possible health risks associated with hormone &lt;br /&gt; replacement, women who are candidates for this therapy may want to &lt;br /&gt; investigate natural alternatives. &#160;Osteoporosis and heart disease can &lt;br /&gt; be prevented with a low-fat vegan (no animal products) diet, and &lt;br /&gt; milder, less potent plant forms of estrogen exist naturally in such &lt;br /&gt; foods as tofu, berries, and citrus fruits. &#160;Those who opt for hormone &lt;br /&gt; replacement therapy can ask their doctors to prescribe one of the &lt;br /&gt; synthetic estrogens. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;- Boycott Ayerst&#039;s parent company, American Home Products / Whitehall &lt;br /&gt; Laboratories, manufacturer of Dristan, Advil, Chef Boyardee, and many &lt;br /&gt; other products. &#160;Also, write to Robert Essner, President, Wyeth-Ayerst &lt;br /&gt; Laboratories, P.O. Box 8299, Philadelphia, P.A. 19101, 215-971-5823 to &lt;br /&gt; voice your protest. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;- Write to the Manitoba government (The Honourable Hananne Cerilli, &lt;br /&gt; Room 234, Legislative Building, Winnipeg, Manitoba R3C 0V8, Canada, &lt;br /&gt; 204-945-1567), protesting their funding of Ayerst&#039;s expansion and &lt;br /&gt; telling them you will not visit the province as long as it continues &lt;br /&gt; to fund cruelty to horses. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;-You can also send away to PETA (P.O. Box 42516, Washington, DC 20015, &lt;br /&gt; (301) 770-PETA ) for copies of the brochure that this information was &lt;br /&gt; taken from to help spread the news (the brochure also includes &lt;br /&gt; information on natural approaches to hormone shifts and synthetic &lt;br /&gt; hormones). &lt;br /&gt; &lt;/p&gt;&lt;p&gt;--------------------End Original Message---------------------------- &lt;br /&gt; &lt;/p&gt;&lt;p&gt;Further suggestion: &lt;br /&gt; &lt;/p&gt;&lt;p&gt;-Call Women&#039;s International Pharamacy at (800) 279-5708 for &lt;br /&gt; alternative natural estrogen cream (Tri-Est) balanced to protect &lt;br /&gt; against breast cancer. &#160;Testosterone gel and natural progesterone &lt;br /&gt; also available. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;---------------------------------------------------------------------- &lt;br /&gt; &lt;/p&gt;&lt;p&gt;Date: &#160; &#160;Sat, 16 Jul 1994 10:31:19 +0000 &lt;br /&gt; From: &#160; &#160;Michael Traub &lt;tr...@BTCS.BT.CO.UK&gt; &lt;br /&gt; Subject: Horse Urine and Hot Flashes (fwd) &lt;br /&gt; &lt;/p&gt;&lt;p&gt;The following article appeared in the June 1994 (Volume &lt;br /&gt; 1, Number 2) issue of Bulletin, a publication of the &lt;br /&gt; Animal Protection Institute (API). For further &lt;br /&gt; information about API, call 1-800-348-7387. &lt;br /&gt; =========================================== &lt;br /&gt; Horse Urine and Hot Flashes &lt;br /&gt; &lt;/p&gt;&lt;p&gt;As many as 90,000 foals a year are slaughtered because &lt;br /&gt; they are the unwanted &quot;by-product&quot; of a multi-million- &lt;br /&gt; dollar drug industry. The foals&#039; mothers endure a bleak &lt;br /&gt; life on a production line for most of their pregnant &lt;br /&gt; months. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;That&#039;s what API found out when it investigated &lt;br /&gt; conditions on farms that supply one drug company with &lt;br /&gt; the urine of pregnant mares. The urine is used by &lt;br /&gt; Wyeth-Ayerst Laboratories to manufacture Premarin, an &lt;br /&gt; estrogen (hormone) replacement drug used by millions of &lt;br /&gt; post-menopausal women. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;In the pregnant mare urine (PMU) industry, this abuse &lt;br /&gt; of the mares and their foals is overshadowed by the &lt;br /&gt; huge profits to be made. In 1992, sales of Premarin &lt;br /&gt; amount to $642 million, accounting for 14 percent of &lt;br /&gt; Wyeth-Ayerst&#039;s $4.5 billion revenue. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;Five hundred PMU farms in North Dakota and Manitoba &lt;br /&gt; (Canada) supply the urine for Wyeth-Ayerst&#039;s processing &lt;br /&gt; plant in Brandon, Manitoba. The farms average 300 &lt;br /&gt; horses each. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;Four months into her pregnancy, the mare is brought &lt;br /&gt; into a stall and fitted with a catheter or a collection &lt;br /&gt; cup. (A cup attached to the catheter collects her &lt;br /&gt; urine.) This is how she will spend the next 7 months. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;So that her urine will be as concentrated as possible, &lt;br /&gt; she receives only 5 gallons of water per day. (Up to &lt;br /&gt; $17 per gallon will be paid for the urine.) Normal &lt;br /&gt; water intake for a horse is 12 to 15 gallons per day; &lt;br /&gt; pregnant horses usually require more. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;After the mare gives birth in late March or early &lt;br /&gt; April, she will have two months with her foal to wean &lt;br /&gt; it. Then she is impregnated again. Her foal is sold to &lt;br /&gt; the slaughterhouse. (Only a handful of the foals are &lt;br /&gt; spared slaughter.) By September, the mare is back in &lt;br /&gt; her stall and on the catheter. &lt;br /&gt; &lt;/p&gt;&lt;p&gt;On the worst farms, the stalls are so narrow the mares &lt;br /&gt; can&#039;t turn around or lie down. Dr. Marc W. Deitch, &lt;br /&gt; Wyeth-Ayerst&#039;s Vice President, Medical Affairs and &lt;br /&gt; Medical Director, has apparently never seen nor heard &lt;br /&gt; of the worst farms. &quot;Horses are in now way mistreated,&quot; &lt;br /&gt; says his form-letter response to all queries about the &lt;br /&gt; abuse of the pregnant mares. &quot;The farmers provide &lt;br /&gt; temperature-controlled stalls that are large enough for &lt;br /&gt; the mares to move about and lie down comfortably.&quot; &lt;br /&gt; &lt;/p&gt;&lt;p&gt;On the worst farms, the mare wears a catheter and a &lt;br /&gt; collection cup. Not so, maintains Dr. Deitch: &quot;The
  ...&lt;/p&gt;&lt;p&gt; read more &#187;
  
  &lt;/p&gt;</description>
		<content:encoded><![CDATA[<p>In article &lt;Cun2AA&#8230;.@tfs.com&gt;, <a href="mailto:poy...@tfs.com">poy&#8230;@tfs.com</a> (David Poyner) says: <br /> 
<p>&gt;Nancy VonStein (nvonst&#8230;@cc.memphis.edu) wrote: <br /> &gt;: There was an article posted here about a month ago about the collection <br /> &gt;: of Premarin. &nbsp;I thought I had kept it but can&#8217;t find it now. &nbsp;If anyone <br /> &gt;: can send me that article, I would appreciate it greatly.  </p>
<p>&gt;I heard the horror story second-hand. It&#8217;s made from mares&#8217; urine and the <br /> &gt;poor things are kept in cages in Canada, yes? I&#8217;d appreciate a re-post if <br /> &gt;anyone could oblige. </p>
<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212; <br /> Subject: PETA Article On Abuse of Horses To Produce Premarin  </p>
<p>Premarin stands for PREgnant MARes UrINe.  </p>
<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211; Message Contents &#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212; &nbsp; &nbsp; &#8211;  </p>
<p>Taken from PETA&#8217;s &quot;Premarin Menopause Drug Nightmare&quot; brochure.  </p>
<p>As the &quot;Baby Boomer&quot; generation matures, and more and more women find <br /> themselves undergoing &quot;The change of life,&quot; many will be advised by <br /> their doctors to take an estrogen replacement drug to alleviate <br /> menopausal symptoms. &nbsp;But the drug most commonly prescribed has at <br /> least one ugly side effect: cruelty.  </p>
<p>The drug is Premarin, an estrogen substitute extracted from the urine <br /> of pregnant mares. &nbsp;It is routinely prescribed for women who have had <br /> hysterectomies or are experiencing menopausal symptoms, and also for <br /> post-menopausal women to prevent osteoporosis and heart disease. &nbsp;With <br /> an estimated eight million women currently taking the drug, and some <br /> 43,000,000 women entering menopause,, the pregnant mare urine (PMU) <br /> industry is booming.  </p>
<p>While this spells profits for Canada-based Ayerst Organics, Inc., the <br /> world&#8217;s only producer of PMU, it also spells misery and death for <br /> hundreds of thousands of horses and foals.  </p>
<p>To produce the drug, mares are impregnated, then catheterized or fitted <br /> with a rubber collection cup attached to a hose. &nbsp;Because allowing <br /> mares out to pasture would mean losing some of their precious urine, <br /> they are forced to stand on concrete floors in stalls measuring just 8 <br /> feet long and 3.5 to 5 feet wide for most of their 11-month <br /> pregnancies.  </p>
<p>For more than half the year &#8212; from September to April &#8212; the mares <br /> are unable to take more than a step in any direction, the narrowness <br /> of their stall preventing even such simple movements ads turning <br /> around or lying down properly. &nbsp;Farmers who have leased their horses <br /> to PMU facilities report mares returning crippled and in poor health, <br /> and one former farm employee documented several deaths on the Manitoba <br /> farm where he worked.  </p>
<p>After giving birth, the mares are allowed only 2 months to pasture <br /> with their foals, during which time they are reimpregnated, then <br /> separated from their babies, and put back on the production line.  </p>
<p>Like calves taken away from their &quot;dairy cow&quot; mothers to be raised for <br /> veal, the mares&#8217; foals are merely a &quot;by-product&quot; of PMU production. <br /> Some are killed immediately, others are kept as replacements for <br /> worn-out mares or to expand production; &nbsp;the majority are sold when <br /> they are about four months old, sent to feedlots to be fattened, and <br /> then slaughtered.  </p>
<p>The cruelty of the PMU industry has caused an outcry from North <br /> Americans, including animal rights activists and women&#8217;s groups. <br /> Problems with the manufacturing process, especially the disposal of <br /> its foul-smelling waste products, worry Canadian environmentalists <br /> and legislators. &nbsp;Proposed expansion at Ayerst&#8217;s Manitoba production <br /> facility threatens to overwhelm and already taxed sewage treatment <br /> system. &nbsp;In addition, according to Marianne Cerilli, member of the <br /> Legislative Assembly and Environment Critic for the Canadian New <br /> Democratic Party, the expansion has &quot;serious consequences for the <br /> Assinboine River, a river that many Manitobans use as a drinking water <br /> source.&quot; &nbsp;Hormone therapy itself is coming under increasing scrutiny <br /> because of possible health risks. &nbsp;Studies have shown that women on <br /> hormone replacement drugs have an increased risk of gall bladder <br /> disease and endometrial and breast cancers and suffer a range of side <br /> effects, such as water retention, cramps, and headaches.  </p>
<p>Since synthetic estrogen can now be manufactured inexpensively, <br /> collecting PMU is an antiquated method of producing estrogen. <br /> Premarin is the only menopause drug still made with animal-derived <br /> estrogen, and other synthetic estrogens, such as Estradiol <br /> Transdermal System, Estradiol tablets, Estropipate, and Estone, are <br /> equally effective.  </p>
<p>In response to Canadian animal protectionists, who were success ful in <br /> shutting down the PMU industry in Ontario during the 1970&#8217;s, the <br /> industry devised a Recommended Code of Practice, which outlines basic <br /> care for horses used for urine production. &nbsp;However, this code merely <br /> contains recommendations &#8212; no farmer is required to follow them &#8212; <br /> and even these basic standards are so weak they fail to provide <br /> horses with even minimal protection.  </p>
<p>In 1993, an estimated 75,000 mares on 485 farms throughout Canada and <br /> North Dakota were confined for urine collection, giving birth to as <br /> many as 90,000 foals &#8212; and the number may triple in the next few <br /> years if women continue to want non-synthetic treatments. &nbsp;Already, <br /> another 1,200 farms have applied to produce PMU, for which they are <br /> paid up to $17 a gallon. &nbsp;Ayerst is preparing for a $100 million <br /> expansion of its facilities in Manitoba with the aid of $20 million <br /> form the Canadian government.  </p>
<p>WHAT YOU CAN DO: <br /> =-=-=-=-=-=-=-=  </p>
<p>- Write a simple letter to a health/women&#8217;s magazine and your local <br /> paper explaining how mare&#8217;s urine is acquired an that there are safe <br /> synthetics available.  </p>
<p>- Because of th possible health risks associated with hormone <br /> replacement, women who are candidates for this therapy may want to <br /> investigate natural alternatives. &nbsp;Osteoporosis and heart disease can <br /> be prevented with a low-fat vegan (no animal products) diet, and <br /> milder, less potent plant forms of estrogen exist naturally in such <br /> foods as tofu, berries, and citrus fruits. &nbsp;Those who opt for hormone <br /> replacement therapy can ask their doctors to prescribe one of the <br /> synthetic estrogens.  </p>
<p>- Boycott Ayerst&#8217;s parent company, American Home Products / Whitehall <br /> Laboratories, manufacturer of Dristan, Advil, Chef Boyardee, and many <br /> other products. &nbsp;Also, write to Robert Essner, President, Wyeth-Ayerst <br /> Laboratories, P.O. Box 8299, Philadelphia, P.A. 19101, 215-971-5823 to <br /> voice your protest.  </p>
<p>- Write to the Manitoba government (The Honourable Hananne Cerilli, <br /> Room 234, Legislative Building, Winnipeg, Manitoba R3C 0V8, Canada, <br /> 204-945-1567), protesting their funding of Ayerst&#8217;s expansion and <br /> telling them you will not visit the province as long as it continues <br /> to fund cruelty to horses.  </p>
<p>-You can also send away to PETA (P.O. Box 42516, Washington, DC 20015, <br /> (301) 770-PETA ) for copies of the brochure that this information was <br /> taken from to help spread the news (the brochure also includes <br /> information on natural approaches to hormone shifts and synthetic <br /> hormones).  </p>
<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8211;End Original Message&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-  </p>
<p>Further suggestion:  </p>
<p>-Call Women&#8217;s International Pharamacy at (800) 279-5708 for <br /> alternative natural estrogen cream (Tri-Est) balanced to protect <br /> against breast cancer. &nbsp;Testosterone gel and natural progesterone <br /> also available.  </p>
<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-  </p>
<p>Date: &nbsp; &nbsp;Sat, 16 Jul 1994 10:31:19 +0000 <br /> From: &nbsp; &nbsp;Michael Traub &lt;tr&#8230;@BTCS.BT.CO.UK&gt; <br /> Subject: Horse Urine and Hot Flashes (fwd)  </p>
<p>The following article appeared in the June 1994 (Volume <br /> 1, Number 2) issue of Bulletin, a publication of the <br /> Animal Protection Institute (API). For further <br /> information about API, call 1-800-348-7387. <br /> =========================================== <br /> Horse Urine and Hot Flashes  </p>
<p>As many as 90,000 foals a year are slaughtered because <br /> they are the unwanted &quot;by-product&quot; of a multi-million- <br /> dollar drug industry. The foals&#8217; mothers endure a bleak <br /> life on a production line for most of their pregnant <br /> months.  </p>
<p>That&#8217;s what API found out when it investigated <br /> conditions on farms that supply one drug company with <br /> the urine of pregnant mares. The urine is used by <br /> Wyeth-Ayerst Laboratories to manufacture Premarin, an <br /> estrogen (hormone) replacement drug used by millions of <br /> post-menopausal women.  </p>
<p>In the pregnant mare urine (PMU) industry, this abuse <br /> of the mares and their foals is overshadowed by the <br /> huge profits to be made. In 1992, sales of Premarin <br /> amount to $642 million, accounting for 14 percent of <br /> Wyeth-Ayerst&#8217;s $4.5 billion revenue.  </p>
<p>Five hundred PMU farms in North Dakota and Manitoba <br /> (Canada) supply the urine for Wyeth-Ayerst&#8217;s processing <br /> plant in Brandon, Manitoba. The farms average 300 <br /> horses each.  </p>
<p>Four months into her pregnancy, the mare is brought <br /> into a stall and fitted with a catheter or a collection <br /> cup. (A cup attached to the catheter collects her <br /> urine.) This is how she will spend the next 7 months.  </p>
<p>So that her urine will be as concentrated as possible, <br /> she receives only 5 gallons of water per day. (Up to <br /> $17 per gallon will be paid for the urine.) Normal <br /> water intake for a horse is 12 to 15 gallons per day; <br /> pregnant horses usually require more.  </p>
<p>After the mare gives birth in late March or early <br /> April, she will have two months with her foal to wean <br /> it. Then she is impregnated again. Her foal is sold to <br /> the slaughterhouse. (Only a handful of the foals are <br /> spared slaughter.) By September, the mare is back in <br /> her stall and on the catheter.  </p>
<p>On the worst farms, the stalls are so narrow the mares <br /> can&#8217;t turn around or lie down. Dr. Marc W. Deitch, <br /> Wyeth-Ayerst&#8217;s Vice President, Medical Affairs and <br /> Medical Director, has apparently never seen nor heard <br /> of the worst farms. &quot;Horses are in now way mistreated,&quot; <br /> says his form-letter response to all queries about the <br /> abuse of the pregnant mares. &quot;The farmers provide <br /> temperature-controlled stalls that are large enough for <br /> the mares to move about and lie down comfortably.&quot;  </p>
<p>On the worst farms, the mare wears a catheter and a <br /> collection cup. Not so, maintains Dr. Deitch: &quot;The<br />
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