Re: YOHIMBE

LITTLELABS (littlel…@aol.com) wrote:

: I am looking for information on what is known of the beneficial health
: effects of Yohimbe root and possible toxic side effects.  It seems to be a
: common ingredient in men vitamins at the health food store.  Does it make
: you horny or something?

10 Responses to “Re: YOHIMBE”

  1. admin says:

    In article <3j3rb8$…@kaiwan009.kaiwan.com>,

    richa…@kaiwan009.kaiwan.com (Richard Armenteros) wrote:
    >LITTLELABS (littlel…@aol.com) wrote:
    >: I am looking for information on what is known of the beneficial health
    >: effects of Yohimbe root and possible toxic side effects.  It seems to be a
    >: common ingredient in men vitamins at the health food store.  Does it make
    >: you horny or something?

    I’m not a pharmacologist, or even a scientifically trained person ..SO….
    what I say may be wrong and I’d be happy to be corrected  … BUT I’m
    pretty sure on this one.  Yohimbe is a tropical plant, I believe a vine.
    Its active ingredient (or one of them, at any rate) is available by
    prescription in the form of Yohimbine Hydrocloride. One of its major
    properties is that it is a vasodilator. In some cases of impotance the
    vasodilating effects of yohimbine-hydrocloride can help with erectile
    problems.  Some doctors have used this drug to treat erectile problems
    associated with the SSRI drugs such as Prozac and Zoloft. A psychiatrist I
    know says that in those cases it’s effective about half the time. I
    believe the form found in vitamins is probably just the raw herb. Like
    many herbs on the market out there it contains powerful compounds
    (otherwise..why take it?) and should be used with discretion and care.
    Just because it’s an herb and available on the market doesn’t mean it
    should be used willy-nilly.

  2. admin says:

    Steve Klarer (kla…@shore.net) wrote:

    : In article <3j3rb8$…@kaiwan009.kaiwan.com>,
    : richa…@kaiwan009.kaiwan.com (Richard Armenteros) wrote:

    : >LITTLELABS (littlel…@aol.com) wrote:

    : >: I am looking for information on what is known of the beneficial health
    : >: effects of Yohimbe root and possible toxic side effects.  It seems to be a
    : >: common ingredient in men vitamins at the health food store.  Does it make
    : >: you horny or something?

    : I’m not a pharmacologist, or even a scientifically trained person ..SO….
    : what I say may be wrong and I’d be happy to be corrected  … BUT I’m
    : pretty sure on this one.  Yohimbe is a tropical plant, I believe a vine.
    : Its active ingredient (or one of them, at any rate) is available by
    : prescription in the form of Yohimbine Hydrocloride. One of its major
    : properties is that it is a vasodilator. In some cases of impotance the
    : vasodilating effects of yohimbine-hydrocloride can help with erectile
    : problems.  Some doctors have used this drug to treat erectile problems
    : associated with the SSRI drugs such as Prozac and Zoloft. A psychiatrist I
    : know says that in those cases it’s effective about half the time. I
    : believe the form found in vitamins is probably just the raw herb. Like
    : many herbs on the market out there it contains powerful compounds
    : (otherwise..why take it?) and should be used with discretion and care.
    : Just because it’s an herb and available on the market doesn’t mean it
    : should be used willy-nilly.

       The active compound in yohimbe, as stated, is the alkaloid, yohimbine.
    Yohimbine is a alpha 2 adrenergic blocker, which acts by increasing the
    cholinergic
    response and decreasing the adrenergic (ADRENALINE) response.  Yohimbine
    can cause CNS stimulation: increased blood pressure, increased heart rate,
    etc.  
       Yohimbine is used for impotence due to its effect on the cholinergic
    system, which is believed to be involved in penile erection.  Some studies
    have shown that yohimbine is thermogenic, thus it may be useful in weightloss.
       Any over-the -counter product that contains yohimbe only contains the
    plant, which in the majority of cases does not contain adequate amounts of
    yohimbine to be effective.

  3. admin says:

    In message ID <klarer-0803952130170…@slip-0-1.shore.net> on 3/9/95, Steve

    Klarer wrote:

    : I’m not a pharmacologist, or even a scientifically trained person
    : ..SO…. what I say may be wrong and I’d be happy to be corrected
    : … BUT I’m pretty sure on this one.  Yohimbe is a tropical plant, I
    : believe a vine.  Its active ingredient (or one of them, at any rate)
    : is available by prescription in the form of Yohimbine Hydrocloride.
    : One of its major properties is that it is a vasodilator. In some
    : cases of impotance the vasodilating effects of
    : yohimbine-hydrocloride can help with erectile problems.  Some
    : doctors have used this drug to treat erectile problems associated
    : with the SSRI drugs such as Prozac and Zoloft. A psychiatrist I know
    : says that in those cases it’s effective about half the time. I
    : believe the form found in vitamins is probably just the raw herb.

    This is very dangerous. Prozac and Zoloft are both equivalent to Heart Yang
    Boosters (Warming, Spirit-supporting herbals), and Yohimbe is very Hot. This
    kind of combination is ruinous to long-term health. Beware!

    P_Iann…@lamg.com (Paul Iannone, P.O.B. 66843, L.A., CA 90066).

  4. admin says:

    Subject: Re: Wild Yam Extract
    From: Steve Dyer, d…@spdcc.com
    Date: Thu, 2 Mar 1995 05:04:50 GMT

    - Hide quoted text — Show quoted text -

    In article <D4srFz….@spdcc.com> Steve Dyer, d…@spdcc.com writes:
    >In article <3j2lbn$…@brtph500.bnr.ca>, Emily Smith <emi…@bnr.ca>
    wrote:
    >>Has anyone tried using Wild Yam Extract (cream) for luteal phase
    problems?
    >>If so, I’d be interested in hearing from you.

    >If you think this is going to have any effect on your reproductive cycle
    >because this it presumably has "steroid precursors", you’re wasting your
    time.
    >You see, the term "steroid" is very generic–there are lots of compounds
    in
    >all sorts of plants which contain (inactive) steroids, sterols, saponins,
    >and related chemicals.  The hormones your body makes also contain the
    same
    >chemical skeleton, though what makes them active (and what makes so many
    >superficially related chemicals act so differently), is the particular
    >substituents on the steroid structure.  That’s why eating eggs, which are
    >loaded with cholesterol, won’t "cure" female, male or adrenal
    insufficiency.
    >Neither will any other non-hormonal sterol, such as you might find in
    yams.

    >The hucksters who push this stuff rely on the fact that most people
    >aren’t trained to recognize pseudo-scientific nonsense when it’s
    >put before them.  Don’t waste your money on this stuff.

    >–
    >Steve Dyer
    >d…@ursa-major.spdcc.com

    True, true.  There is, however, no arguing the simple, bald fact that many
    women are helped by the use of "Wild Yam" cremes, extracts, etc.  Most of
    those marketed (as opposed to a simple pharmaceutical-grade tincture of
    Dioscorea villosa which has rather unrelated value as a mild prostaglandin
    inhibitor) work very well for MOST women (some have adverse reactions, and
    sensibly cease its use).  The value, particularly in early menopause, when
    the corpus luteum fragility is often an early sign of the transition, lay
    with a secondary compound used in these OTC products.

    They usually contain Natural Progesterone.  Period.  Real progesterone.  
    Usually pharmaceutically synthesized from soy bean phytosterols (cheap raw
    materials in the world market, some products use progestrone derived from
    pregnant mare urine…all or purchased from the drug industry, and
    available
    OTC because of an older FDA ruling that classed topical use as cosmetic,
    not medical.  The term "Natural" simply means that it is not an orally
    active drug analog that has been engineered to get past the stomach and
    liver and retain progesterone activity.  Oral progesterone is one of
    several
    purely synthetic testesterone-related compounds.  

    Natural Progesterone is, however, identical to luteal progesterone.  Taken
    orally it is 99% digested into nutrients.  It is only active when
    injected;
    and when used topically, it is stored awhile in SOME subcutaneous fat and
    slowly released into the bloodstream.

    This is why Wild Yam preparations often help…the OTHER stuff down the
    constituent list…Natural Progesterone.

    There is little question that this mode of application has many attractive
    advantages…no prescription or doctor costs, and it ENDS in the liver
    (the way steroid hormones are meant to), rather than STARTING in the liver
    as the result of absorption from the gut.

    The downside is…it is STILL an exogenous hormone, derived from the
    pharmaceutical industry.  It does what it does, no precursors need apply,
    and this whole subset of the "herb industry" (supplying pharmaceuticals
    because of an FDA loophole) is simply selling the image of self-help,
    instead supplying hormone therapy, and without allowing women to make
    choices based on fact.  They are being lied to.

    (Nothing new about that, however)

    Michael Moore (hrbmo…@rt66.com)

    (GOPHER and WWW)
      gopher://president.oit.unc.edu:70/11/../.pub/academic/medicine
      /alternative-healthcare/Southwest-School-of-Botanical-Medicine
    (ANONYMOUS FTP)
      sunsite.unc.edu     /pub/academic/medicine/alternative-healthcare/
      Southwest-School-of-Botanical-Medicine
    —————————————————————–
    All the SWSBM teaching and clinical manuals, JPEGs of Medicinal Plant
    photographs and class announcements can be obtained at these sites.

  5. admin says:

    > True, true.  There is, however, no arguing the simple, bald fact that many
    > women are helped by the use of "Wild Yam" cremes, extracts, etc.  Most of
    > those marketed (as opposed to a simple pharmaceutical-grade tincture of
    > Dioscorea villosa which has rather unrelated value as a mild prostaglandin
    > inhibitor) work very well for MOST women (some have adverse reactions, and
    > sensibly cease its use).  The value, particularly in early menopause, when
    > the corpus luteum fragility is often an early sign of the transition, lay
    > with a secondary compound used in these OTC products.

    > They usually contain Natural Progesterone.  Period.  Real progesterone.  

    Could anyone list OTC products which contain natural progesterone or if
    any contain natural estrogen?

  6. admin says:

    - Hide quoted text — Show quoted text -

    In article <3j6arl$…@mack.rt66.com>, Michael Moore <hrbmo…@rt66.com> wrote:
    > Subject: Re: Wild Yam Extract
    > From: Steve Dyer, d…@spdcc.com
    > Date: Thu, 2 Mar 1995 05:04:50 GMT
    > In article <D4srFz….@spdcc.com> Steve Dyer, d…@spdcc.com writes:
    > >In article <3j2lbn$…@brtph500.bnr.ca>, Emily Smith <emi…@bnr.ca>
    > wrote:
    > >>Has anyone tried using Wild Yam Extract (cream) for luteal phase
    > problems?
    > >>If so, I’d be interested in hearing from you.

    > >…
    > >Neither will any other non-hormonal sterol, such as you might find in
    > yams.

    > >The hucksters who push this stuff rely on the fact that most people
    > >aren’t trained to recognize pseudo-scientific nonsense when it’s
    > >put before them.  Don’t waste your money on this stuff.

    > >–
    > >Steve Dyer
    > >d…@ursa-major.spdcc.com

    > True, true.  There is, however, no arguing the simple, bald fact that many
    > women are helped by the use of "Wild Yam" cremes, extracts, etc.  …

    > Natural Progesterone is, however, identical to luteal progesterone.  Taken
    > orally it is 99% digested into nutrients.  It is only active when
    > injected;
    > and when used topically, it is stored awhile in SOME subcutaneous fat and
    > slowly released into the bloodstream.

    > This is why Wild Yam preparations often help…the OTHER stuff down the
    > constituent list…Natural Progesterone….

    > Michael Moore (hrbmo…@rt66.com)

    > (GOPHER and WWW)
    >   gopher://president.oit.unc.edu:70/11/../.pub/academic/medicine
    >   /alternative-healthcare/Southwest-School-of-Botanical-Medicine
    > (ANONYMOUS FTP)
    >   sunsite.unc.edu     /pub/academic/medicine/alternative-healthcare/
    >   Southwest-School-of-Botanical-Medicine
    > —————————————————————–
    > All the SWSBM teaching and clinical manuals, JPEGs of Medicinal Plant
    > photographs and class announcements can be obtained at these sites.

    How can natural progesterone be obtained commercially–under what name(s)
    and at what locations (pharmacies?, herb shops?)  I would like to try it
    as I have just suffered through terrible side effects from a synthetic
    progesterone.  My suffering lead me to an article which mentioned natural
    progesterone as a treatment for hormone imbalance.  Any help from any one
    will be appreciated.  E-mail is OK to grans…@best.com.

    Jennifer Gransaull
    grans…@best.com

  7. admin says:

    You can buy ProGest or other mexican yam creams at healthfood stores or
    co-ops. Mexican yam extract IS natural progesterone. These creams are
    usually 3% yam extract. I use ProGest myself. I *think* there may be an
    estrogen cream, but I can’t remember what it’s called, and as far as I
    know, you can buy it only from places like Women’s International
    Pharmacy, by mailorder.

    As far as "natural estrogen" goes, soy products contain natural estrogen,
    so if you eat soy milk, tofu, etc., you’re ingesting natural estrogen.

    Hope this helps,
    Anne Washburn
    qua…@vnet.net

  8. admin says:

    Subject: Re: Wild Yam Extract
    From: Anne Washburn, qua…@vnet.net
    Date: 6 Mar 1995 16:17:20 GMT
    In article <3jfcig$…@ralph.vnet.net> Anne Washburn, qua…@vnet.net
    writes:

    >You can buy ProGest or other mexican yam creams at healthfood stores or
    >co-ops. Mexican yam extract IS natural progesterone. These creams are
    >usually 3% yam extract. I use ProGest myself. I *think* there may be an
    >estrogen cream, but I can’t remember what it’s called, and as far as I
    >know, you can buy it only from places like Women’s International
    >Pharmacy, by mailorder.

    >As far as "natural estrogen" goes, soy products contain natural
    estrogen,
    >so if you eat soy milk, tofu, etc., you’re ingesting natural estrogen.

    >Hope this helps,
    >Anne Washburn
    >qua…@vnet.net

    Sorry, but I know FOR A FACT that ProGest (and most of the other similar
    topical creams) contains pharmaceutical progesterone.  Please believe me.
    I think the topical use is often a FAR better approach…but it is NOT
    Wild Yam, Mexican Yam, or any other crude or galenic (herbal) preparation
    that does the stuff…it’s Real Progesterone.  As for the foods you
    mentioned, they are NOT physiologic estrogens, but they contain plant
    steroids.  The ONLY precursor or crude substance any of us can use to
    make OUR steroid hormones…is low-density cholesterol or recycled
    steroids.  There are a FEW herbs with crude hormone-mimicking effects.
    A few of these, like Licorice, can be useful.  Most are not.  If a
    woman has low estrogen or progesterone levels it is because the
    metabolic STIMULUS is low.  Metabolic approaches, using diet, herbs,
    visualization, body work, etc. are the only native ways to elevate
    hormones, presuming that the low levels are WRONG.  If soybeans supply
    necessary nutrients that are lacking, or the change in diet results in
    a change in metabolism (usually the case) then FINE.  But it isn’t
    because there is a "hormone" in soybeans.  A lot of the writings on
    the subject are pseudo-science and warped medicine as viewed in a
    fun-house mirror.  Like I say, some topical steroid use SEEMS to be
    a far preferable approach (lacking any pathology).  But it isn’t
    "natural"…it just works sometimes.  Mexican Yam was, 50 years ago,
    chosen as a cheap source of a saponin that, using a purely synthetic
    avenue, could be transfromed into progesterone.  

    WE don’t make progesterone that way in our bodies.  The saponin from
    Mexican Yam would act as an irritating laxative.  If we continued, it
    would start to weaken the bonds between red blood cells and hemoglobin
    and we would start getting hemolytic anemia.  Making progesterone from
    Mexican Yam extracts can be done in the pharmaceutical lab, but it has
    NO relationship (Marker degradation method) to OUR synthesis of ANY
    of our steroid hormones.

    Michael Moore (hrbmo…@rt66.com)

    (GOPHER and WWW)
      gopher://president.oit.unc.edu:70/11/../.pub/academic/medicine
      /alternative-healthcare/Southwest-School-of-Botanical-Medicine
    (ANONYMOUS FTP)
      sunsite.unc.edu     /pub/academic/medicine/alternative-healthcare/
      Southwest-School-of-Botanical-Medicine
    —————————————————————–
    All the SWSBM teaching and clinical manuals, JPEGs of Medicinal Plant
    photographs and class announcements can be obtained at these sites.

  9. admin says:

    Steve Dyer (d…@spdcc.com) wrote:

    : If you think this is going to have any effect on your reproductive cycle
    : because this it presumably has "steroid precursors", you’re wasting your time.
    : You see, the term "steroid" is very generic–there are lots of compounds in
    : all sorts of plants which contain (inactive) steroids, sterols, saponins,
    : and related chemicals.  The hormones your body makes also contain the same
    : chemical skeleton, though what makes them active (and what makes so many
    : superficially related chemicals act so differently), is the particular
    : substituents on the steroid structure.  That’s why eating eggs, which are
    : loaded with cholesterol, won’t "cure" female, male or adrenal insufficiency.
    : Neither will any other non-hormonal sterol, such as you might find in yams.

    I’m confused now.  I have in my hand the Feb. 1995 copy of the Harvard
    Women’s Health Watch newsletter which mentions that natural progesterone
    is extracted from yams.  They also mention that this ‘natural
    progesterone’ is generally not available in the US. They aren’t exactly
    wild-eyed radicals and I’ve generally found them to have their shit
    together re: pharmacology.  

    The article also goes on to mention that it was shown in in PEPI
    (Postmenopausal Estrogen/Progestin Interventions) Trial that women who
    took estrogen combined with natural progesterone had higher HDL levels
    than women who took synthetic progestin.  This study was published in the Jan. 18, 1995
    issue of JAMA according to the article.

    ———————————————————————–
               Camilla Cracchiolo, RN   cami…@primenet.com

            Shrine of the Cybernetic Madonna BBS  213-766-1356
    "The board that Hates Rush Limbaugh *and* Newt Gingrich With A Passion"
    ———————————————————————–

  10. admin says:

    In article <3jlkdc$…@news.primenet.com>,
    Camilla Cracchiolo <cami…@primenet.com> wrote:

       >I’m confused now.  I have in my hand the Feb. 1995 copy of the Harvard
       >Women’s Health Watch newsletter which mentions that natural progesterone
       >is extracted from yams.  They also mention that this ‘natural
       >progesterone’ is generally not available in the US. They aren’t exactly
       >wild-eyed radicals and I’ve generally found them to have their shit
       >together re: pharmacology.  

    It might be synthesized from the dioscin found in yams, since that’s a
    cheap source of raw sterol material to start with, but "extracted" isn’t
    quite the right word.  That’s like saying that plastic is "extracted"
    from crude oil.  Well, sure, if you skip a "few" steps.

    If you’re interested, why not ask the author of that article where
    they got the information about yams, and what they really meant?
    I suspect you’re reading very lazy lay usage.

       >The article also goes on to mention that it was shown in in PEPI
       >(Postmenopausal Estrogen/Progestin Interventions) Trial that women who
       >took estrogen combined with natural progesterone had higher HDL levels
       >than women who took synthetic progestin.  This study was published in
       >the Jan. 18, 1995 issue of JAMA according to the article.

    Whatever the effects of progesterone supplementation might be,
    a study of its effects is orthogonal to the question of whether
    yam extract contains progesterone, which it doesn’t.


    Steve Dyer
    d…@ursa-major.spdcc.com